Variations in Parameters of Hepatotoxicity Induced by Anti TB Treatment with Comorbid Acute Viral Hepatitis
نویسندگان
چکیده
Objectives & background: Drug-induced hepatotoxicity (DIH) is a common side effect of anti-TB drugs. Acute viral hepatitis (AVH) may be confounded with chronic alcoholic clinically, biochemically, and histologically (CAH). Place Study: Rashid Latif Medical College Lahore Duration March 2019 to January 2021 Methods: This prospective research examined the acute as contributing confounding factor in patients normal baseline liver function who acquired while taking short-course medication. All patients' blood was analysed for A, B, C, E markers. Results: In 12 80 TB developed hepatitis, virus present. Indicators included delayed onset significant increases aspartate aminotransferase (AST) alanine (ALT), longer period abnormal levels normalise. Conclusions: According our statistics, 15% hepatotoxic had AVH. Before attributing impact medications DIH patients, should evaluated ruled out all endemic-area patients.
منابع مشابه
Role of acute viral hepatitis as a confounding factor in antituberculosis treatment induced hepatotoxicity.
BACKGROUND & OBJECTIVE Drug induced hepatotoxicity (DIH) is an important and commonly encountered adverse effect with antituberculosis (anti-TB) treatment. Acute viral hepatitis (AVH) is an important confounding reason which clinically, biochemically and histologically mimics DIH. METHODS The contributory role of acute viral hepatitis as a confounding factor in patients with normal baseline l...
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ژورنال
عنوان ژورنال: Pakistan Journal of Medical and Health Sciences
سال: 2022
ISSN: ['1996-7195']
DOI: https://doi.org/10.53350/pjmhs22168568